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Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal...
“Colorectal cancer (CRC), like other tumor types, is a highly heterogeneous disease. Within the tumor bulk, intra-tumoral heterogeneity is also ascribable to Cancer Stem Cells (CSCs) subpopulation,...
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(±)-Sativamides A and B, Two Pairs of Racemic Nor-lignanamide Enantiomers...
“(±)-Sativamides A (1) and B (2), two pairs of nor-lignanamide enantiomers featuring a unique benzo-angular triquinane skeleton, were isolated from the fruits of Cannabis sativa (hemp seed). Their...
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Medical Cannabis: The Oncology Nurse’s Role in Patient Education About the...
“Cannabis, also known as marijuana, is legal either medicinally or recreationally in 29 states and the District of Columbia, with a majority of the U.S. adult population now living in states where...
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Targeting the endocannabinoid system as a potential anticancer approach.
“The endocannabinoid system is currently under intense investigation due to the therapeutic potential of cannabinoid-based drugs as treatment options for a broad variety of diseases including cancer....
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Phytochemical Aspects and Therapeutic Perspective of Cannabinoids in Cancer...
“Cannabis sativa L. (Cannabaceae) is one of the first plants cultivated by man and one of the oldest plant sources of fibre, food and remedies. Cannabinoids comprise the plant‐derived compounds and...
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Cannabidiol Induces Cytotoxicity and Cell Death via Apoptotic Pathway in...
“In view of obtaining potential anticancer compounds, we studied the inhibitory activity and the cytotoxic effects of a candidate compound in cancer cells. The cytotoxic effects of cannabidiol (CBD)...
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Direct modulation of the outer mitochondrial membrane channel,...
“Cannabidiol (CBD) is a non-psychoactive plant cannabinoid that inhibits cell proliferation and induces cell death of cancer cells and activated immune cells. Here, we studied the effects of CBD on...
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CBD Enhances the Anticancer Effects of THC
“Δ9-Tetrahydrocannabinol (Δ9-THC) and other cannabinoids can act as direct anticancer agents in multiple types of cancer in culture and in vivo. Cannabidiol Enhances the Inhibitory Effects of...
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Cannabinoid-induced cell death in endometrial cancer cells: involvement of...
“Among a variety of phytocannabinoids, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most promising therapeutic compounds. Besides the well-known palliative effects in cancer patients,...
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Cannabis for vismodegib-related muscle cramps in a patient with advanced...
“Vismodegib is a hedgehog inhibitor drug indicated for metastatic or locally advanced basal cell carcinoma (BCC) that is not fit for surgery or radiation therapy. One of the most common side effects of...
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The current state and future perspectives of cannabinoids in cancer biology.
“To date, cannabinoids have been allowed in the palliative medicine due to their analgesic and antiemetic effects, but increasing number of preclinical studies indicates their anticancer properties....
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Prospective analysis of safety and efficacy of medical cannabis in large...
“Cancer is a major public health problem as the leading cause of death. Palliative treatment aimed to alleviate pain and nausea in patients with advanced disease is a cornerstone of oncology. In 2007,...
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Pascal Biosciences Identifies Molecules in Cannabis That Stimulate the Immune...
“Pascal Biosciences Inc. (TSX.V:PAS) (“Pascal” or the “Company”) announced the Company has discovered certain cannabinoids that enhance the immunogenicity of tumor cells, rendering them more...
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Anti-invasion Effects of Cannabinoids Agonist and Antagonist on Human Breast...
“Studies show that cancer cell invasion or metastasis is the primary cause of death in malignancies including breast cancer. The existence of cancer stem cells (CSCs) in breast cancer may account for...
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Medical cannabis in the treatment of cancer pain and spastic conditions and...
“The use of cannabis for medical purposes has been recently legalised in many countries including the Czech Republic. As a result, there is increased interest on the part of physicians and patients in...
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Suppression of Cisplatin-Induced Vomiting by Cannabis sativa in Pigeons:...
“Cannabis sativa (CS, family Cannabinaceae) has been reported for its anti-emetic activity against cancer chemotherapy-induced emesis in animal models and in clinics. The current study was designed to...
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The use of cannabis in supportive care and treatment of brain tumor
“Anticancer Effects of Cannabinoids may be able to Prolong Life. Cannabinoids are multitarget substances. Currently available are dronabinol (synthetic delta-9-tetrahydrocannabinol, THC), synthetic...
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Cannabis and Anti-Cancer Drugs: Societal Usage and Expected Pharmacological...
“Cannabis is a plant that has been used for centuries to relieve a wide range of symptoms. Since the 1960s, interest in medical research into this plant has grown steadily. Already very popular for...
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INSIGHT ON THE IMPACT OF ENDOCANNABINOID SYSTEM IN CANCER: A REVIEW.
“In the last decades, the endocannabinoid system has attracted a great interest in medicine and cancer disease is probably one of its most promising therapeutic areas. On the one hand, endocannabinoid...
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Hemp shows potential for treating ovarian cancer
“Researchers demonstrate hemp’s ability to slow cancer growth and uncover mechanism for its cancer-fighting ability. Results from some of the first studies to examine hemp’s ability to fight cancer...
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