“Vismodegib is a hedgehog inhibitor drug indicated for metastatic or locally advanced basal cell carcinoma (BCC) that is not fit for surgery or radiation therapy.

One of the most common side effects of vismodegib is muscle cramps which can cause a decrease in quality of life (QoL) and treatment discontinuation. Cannabis is known to improve spasticity (including muscle cramps) in multiple sclerosis patients.”

http://www.jpsmjournal.com/article/S0885-3924(18)30070-8/fulltext

“Medical marijuana for the treatment of vismodegib-related muscle spasm. We report a case of vismodegib-related muscle spasm that was successfully treated with medical marijuana (MM).” http://www.jaadcasereports.org/article/S2352-5126(17)30124-8/fulltext