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The Potential Antinociceptive Effect and Mechanism of Cannabis sativa L....
“Cannabis sativa L. (hemp) is a herbaceous plant rich in cannabinoids with a long history of use in pain treatment. The most well-characterized cannabinoids, cannabidiol (CBD) and...
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Extraction, purification and in vitro assessment of the antioxidant and...
“Policosanols (PCs) are bioactive compounds extracted from different natural waxes. In this work, the purification, characterization and assessment of the antioxidant and anti-inflammatory activity...
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Cannabis and cancer: unveiling the potential of a green ally in breast,...
“Cancer comes in second place on the list of causes of death worldwide. In 2018, the 5-year prevalence of breast cancer (BC), prostate cancer (PC), and colorectal cancer (CRC) were 30%, 12.3%, and...
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Anticancer effect of minor phytocannabinoids in preclinical models of...
“Multiple myeloma (MM) is a blood cancer caused by uncontrolled growth of clonal plasmacells. Bone disease is responsible for the severe complications of MM and is caused by myeloma cells infiltrating...
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The antitumor action of endocannabinoids in the tumor microenvironment of...
“Approximately 80% of all malignant brain tumors are gliomas, which are primary brain tumors. The most prevalent subtype of glioma, glioblastoma multiforme (GBM), is also the most deadly....
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Cannabidiol and Aza-BODIPY Coencapsulation for Photodynamic Therapy...
“Photodynamic therapy (PDT) and cannabidiol (CBD) have been explored for their potential in synergistic cancer treatment. In this study, we employed CBD oil as a lipid phase, encapsulated within...
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Marijuana Use May Be Associated with Reduced Prevalence of Prostate Cancer: A...
“Preclinical evidence indicates the potential anti-tumor capabilities of cannabinoids in prostate cancer (PC). We undertook a cross-sectional study using National Survey on Drug Use and Health data...
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Effect of Cannabis sativa L. extracts, phytocannabinoids and their acetylated...
“Background: There is a need for novel treatments for neuroblastoma, despite the emergence of new biological and immune treatments, since refractory pediatric neuroblastoma is still a medical...
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Identification of Genes Hub Associated with Triple-Negative Breast Cancer and...
“Objective: Triple-negative breast cancer presents a significant challenge in oncology due to its complex treatment and aggressive nature. This subtype lacks common cancer cell receptors like...
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Inflammation and cancer: friend or foe?
“Chronic inflammation plays a crucial role in the onset and progression of pathologies like neurodegenerative and cardiovascular diseases, diabetes, and cancer, since tumor development and chronic...
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Cannabidiol reverts the malignant phenotype of hepatocellular carcinoma cells...
“Cannabidiol (CBD) has antioxidant and anti-inflammatory activities. However, the anti-tumor effect of CBD on hepatocellular carcinoma (HCC) remains unclear. Here, we investigated whether CBD displays...
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Cannabidiol mitigates radiation-induced intestine ferroptosis via...
“Radiation enteritis remains a major challenge for radiotherapy against abdominal and pelvic malignancies. Nevertheless, there is no approved effective therapy to alleviate irradiation (IR)-induced...
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Anti-Cancer and Anti-Proliferative Potential of Cannabidiol: A Cellular and...
“Cannabinoids, the bioactive compounds found in Cannabis sativa, have been used for medicinal purposes for centuries, with early discoveries dating back to the BC era (BCE). However, the increased...
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Chemical compounds, anti-tumor and anti-neuropathic pain effect of hemp...
“Hemp (Cannabis sativa L.), an annual dioecious plant, has shown extensive application in the fields of fibers, food, oil, medicine, etc. Currently, most attention has been paid to the therapeutic...
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The potential of cannabinoids in managing cancer-related anorexia in older...
“Background and objectives: Anorexia of aging (AoA) is a prevalent geriatric syndrome characterized by a multifactorial decline in appetite and reduced food intake associated with the aging process....
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Cheungsam Seed Husk Extract Reduces Skin Inflammation through Regulation of...
“Cannabis contains numerous natural components and has several effects such as anticancer, anti-inflammatory and antioxidant. Cheungsam is a variety of non-drug-type hemp, developed in Korea and is...
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The potential neuroprotective effects of cannabinoids against...
“Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is a shared burden for 68.1% of oncological patients undergoing chemotherapy with Paclitaxel (PTX). The symptoms are intense and...
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Selected phytocannabinoids inhibit SN-38- and cytokine-evoked increases in...
“Irinotecan use is linked to the development of gastrointestinal toxicity and inflammation, or gastrointestinal mucositis. Selected phytocannabinoids have been ascribed anti-inflammatory effects in...
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Cannabidiol Alleviates Oral Mucositis by Inhibiting PI3K/Akt/NF-κB-Mediated...
“Background: Cannabidiol (CBD), extracted from Cannabis sativa, has anticancer, anti-inflammation, and analgesic effects. Nevertheless, its therapeutic effect and the mechanism by which it alleviates...
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Lebanese Cannabis Oil as a Potential Treatment for Acute Myeloid Leukemia: In...
“Ethnopharmacological relevance: The Cannabis sativa L. ssp. indica (Lam.) plant has been historically utilized as a natural herbal remedy for the treatment of several ailments. In Lebanon, cannabis...
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