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Differences in the phospholipid profile of melanocytes and melanoma cells...
“UV radiation inducing mutations in melanocytes might cause melanoma. As changes in lipid composition and metabolism are associated with many types of cancer including skin cancer, we aimed to...
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Identification of phenolic compounds from inflorescences of non-psychoactive...
“Phenolic compounds from Cannabis sativa L. (Cannabaceae family), in particular cannflavins, are known to possess several biological properties. However, their antiproliferative activity, being of...
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Cannabinoids in Medicine: A Multifaceted Exploration of Types, Therapeutic...
“In this review article, we embark on a thorough exploration of cannabinoids, compounds that have garnered considerable attention for their potential therapeutic applications. Initially, this article...
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Cannabis Use Patterns among Patients with Early-Stage Breast Cancer in a...
“Purpose/objective(s): Cannabis use among patients with cancer is an area of great interest given its widespread acceptance despite the lack of supporting clinical data. The absence of data limits the...
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Cannabinoids in Breast Cancer: Differential Susceptibility According to Subtype
“Although cannabinoids have been used for centuries for diverse pathological conditions, recently, their clinical interest and application have emerged due to their diverse pharmacological properties....
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Anti-proliferative effect of Cannabidiol in Prostate cancer cell PC3 is...
“Prostate cancer is the second most frequent cancer diagnosed in men in the world today. Almost all prostate cancers are adenocarcinomas and develop from gland cells. We used the PC3 prostate cancer...
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Cannabidiol Antiproliferative Effect in Triple-Negative Breast Cancer...
“Cannabidiol (CBD) is a non-psychoactive phytocannabinoid that has been discussed for its safety and efficacy in cancer treatments. For this reason, we have inquired into its use on triple-negative...
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Cannabinol inhibits cell growth and triggers cell cycle arrest and apoptosis...
“Cancer is one of the most difficult diseases to treat and cure.” “Cannabinol (CBN), one of the active ingredients from the cannabis plant, is the breakdown molecule of Δ9-tetrahydrocannabinol...
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Reversion of chemoresistance by endocannabinoid-induced ER stress and...
“The difficulty of detection at an early stage and the ease of developing resistance to chemotherapy render ovarian cancer (OVC) difficult to cure. Although several novel cancer therapies have been...
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Cell death induction and intracellular vesicle formation in human colorectal...
“Background: Δ9-Tetrahydrocannabinol (Δ9-THC) is a principal psychoactive extract of Cannabis sativa and has been traditionally used as palliative medicine for neuropathic pain. Cannabidiol (CBD), an...
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The potential protective and therapeutic effects of cannabidiol oil on...
“Background: 7,12-Dimethylbenzanthracene (DMBA) is a member of the polycyclic aromatic hydrocarbon family. It is a member of the polycyclic aromatic hydrocarbon family. It is a mutagenic,...
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Eight Weeks of Daily Cannabidiol Supplementation Improves Sleep Quality and...
“Background: The endocannabinoid system is active in nervous and immune cells and involves the expression of two cannabinoid receptor genes (CB1 and CB2), along with endogenous endocannabinoid...
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In Vitro Antiproliferative Effect of Cannabis Extract PHEC-66 on Melanoma...
“Melanoma, an aggressive form of skin cancer, can be fatal if not diagnosed and treated early. Melanoma is widely recognized to resist advanced cancer treatments, including immune checkpoint...
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Rationalizing a prospective coupling effect of cannabinoids with the current...
“Melanoma is one of the leading fatal forms of cancer, yet from a treatment perspective, we have minimal control over its reoccurrence and resistance to current pharmacotherapies. The endocannabinoid...
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The ameliorative effects of cannabidiol on methotrexate-induced...
“Methotrexate (MTX) is an antineoplastic agent and has neurotoxic effects. It exerts its toxic effect on the brain by triggering inflammation and apoptosis. Cannabidiol (CBD) is an agent known for its...
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Involvement of cannabinoid receptors and adenosine A2B receptor in enhanced...
“Residual cancer cells after radiation therapy may acquire malignant phenotypes such as enhanced motility and migration ability, and therefore it is important to identify targets for preventing...
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The potential of cannabinoids in the treatment of lung cancer
“Introduction: Lung cancer is the number-one cause of death due to neoplasms worldwide. The 5-year overall survival rate is only 22%. In advanced stages, the therapeutic options are limited to...
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Synergistic inhibition of glioblastoma multiforme through an in-silico...
“The primary objective of this study is to uncover novel therapeutic agents for the treatment of Glioblastoma Multiforme (GBM), a highly aggressive form of brain cancer, and Alzheimer’s Disease (AD)....
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Engineering cannabidiol synergistic carbon monoxide nanocomplexes to enhance...
“Although carbon monoxide (CO)-based treatments have demonstrated the high cancer efficacy by promoting mitochondrial damage and core-region penetrating ability, the efficiency was often compromised...
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Medical cannabis for refractory cancer-related pain in a specialised clinical...
“Background and objectives: Cancer-related pain management in advanced stages presents a significant challenge that often requires a multidisciplinary approach. Although advancements in...
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