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Unveiling the Angiogenic Effects of Cannabinoids: Enhancers or inhibitors?

“Cannabinoids are compounds found in the cannabis sativa plant. Cannabinoids, such as delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), have potential therapeutic benefits in various medical...

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The role of cannabidiol in aging

“Aging is usually considered a key risk factor associated with multiple diseases, such as neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden of age-related...

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Advanced multifunctional nano-lipid carrier loaded gel for targeted delivery...

“Non-melanoma skin cancer is one of the most common malignancies reported around the globe. Current treatment therapies fail to meet the desired therapeutic efficacy due to high degree of drug...

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Improving Quality of Life During Chemotherapy: Cannabinoids, Cryotherapy, and...

“There have been significant advances in the treatment of cancer in the past decade. However, patients continue to suffer from significant side effects of antineoplastic agents that greatly affect...

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Genome-Scale Metabolic Reconstruction, Non-Targeted LC-QTOF-MS Based...

“Over the past decades, Colombia has suffered complex social problems related to illicit crops, including forced displacement, violence, and environmental damage, among other consequences for...

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Should oncologists trust cannabinoids?

“Cannabis enjoyed a “golden age” as a medicinal product in the late 19th, early 20th century, but the increased risk of overdose and abuse led to its criminalization. However, the 21st century have...

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Could cannabinoids provide a new hope for ovarian cancer patients?

“It is known that gynecological cancers remain a worldwide problem and as shown by the statistics, there is a need for new gynecological cancer treatments. Cannabinoids, the pharmacologically active...

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Molecular pathway and structural mechanism of human oncochannel TRPV6...

“The calcium-selective oncochannel TRPV6 is an important driver of cell proliferation in human cancers. Despite increasing interest of pharmacological research in developing synthetic inhibitors of...

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CBD-oil as a potential solution in case of severe tamoxifen-related side effects

“Tamoxifen may lead to bothersome side effects contributing to non-compliance and decreased quality of life. Patients searching for relief are increasingly turning to cannabinoids such as CBD-oil....

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Cannabidiol-induced crosstalk of apoptosis and macroautophagy in colorectal...

“Although it has been established that cannabidiol (CBD), the major non-psychoactive constituent of cannabis, exerts antitumoral activities, the exact mechanism(s) via which tumor cells are killed by...

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Cannabidiol Enhances Cabozantinib-Induced Apoptotic Cell Death via...

“Cannabidiol (CBD), a primary constituent in hemp and cannabis, exerts broad pharmacological effects against various diseases, including cancer. Additionally, cabozantinib, a potent multi-kinase...

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Single-cell analyses reveal cannabidiol rewires tumor microenvironment via...

“Colorectal tumors often create an immunosuppressive microenvironment that prevents them from responding to immunotherapy. Cannabidiol (CBD) is a non-psychoactive natural active ingredient from the...

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Oral Tetrahydrocannabinol (THC):Cannabinoid (CBD) Cannabis Extract Adjuvant...

“Objective: To evaluate the effects of tetrahydrocannabinol (THC):cannabinoid (CBD) (1:1) oil in reducing chemotherapy-induced nausea and vomiting (CINV) in gynecologic cancer patients who received...

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Cannabinoids and standardized cannabis extracts inhibit migration, invasion,...

“Background: Breast cancer is the highest incidence of all types of cancer in women, and the cancer metastasis process accounts for a majority of cancer deaths. Two major cannabinoids,...

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Etoricoxib-Cannabidiol Combo: Potential Role in Glioblastoma Treatment and...

“Background: Glioblastoma (GBM) is the most frequently occurring primary malignant central nervous system tumor, with a poor prognosis and median survival below two years. Administration of a...

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Cannabinoids for symptom management in children with cancer: A systematic...

“Background: Despite the widespread use of medical cannabis, little is known regarding the safety, efficacy, and dosing of cannabis products in children with cancer. The objective of this study was to...

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Mechanisms Involved in the Therapeutic Effect of Cannabinoid Compounds on...

“Introduction: Brain tumors have high morbidity and mortality rates, accounting for 1.4% of all cancers. Gliomas are the most common primary brain tumors in adults. Currently, several thera-peutic...

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Rimonabant and Cannabidiol Rewrite the Interactions between Breast Cancer...

“The spread of breast cancer to distant sites is the major cause of death in breast cancer patients. Increasing evidence supports the role of the tumor microenvironment (TME) in breast cancers, and...

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CBD Inhibits In Vivo Development of Human Breast Cancer Tumors

“Inflammation is a critical component of cancer development. Previously, we showed in vitro that IL-1β treatment of non-invasive human breast cancer MCF-7 cells promoted their transition to a...

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Cannabidiol Inhibits the Proliferation and Invasiveness of Prostate Cancer Cells

“Prostate cancer is the fifth leading cause of cancer death in men, responsible for over 375,000 deaths in 2020. Novel therapeutic strategies are needed to improve outcomes. Cannabinoids, chemical...

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