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Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell...
“In spite of the huge advancements in both diagnosis and interventions, hormone refractory prostate cancer (HRPC) remains a major hurdle in prostate cancer (PCa). Metabolic reprogramming plays a key...
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Inhalant cannabidiol impedes tumor growth through decreased tumor stemness...
“Lung cancer remains the most chronic form of cancer and the leading cause of cancer mortality in the world. Despite significant improvements in the treatment of lung cancer, the current therapeutic...
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The evolution of cannabinoid receptors in cancer
“Cannabis sativa (cannabis) has been used as a therapeutic treatment for centuries treating various diseases and disorders. However, racial propaganda led to the criminalization of cannabis in the...
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Cannabidiol regulates apoptosis and autophagy in inflammation and cancer: A...
“Cannabidiol (CBD) is a terpenoid naturally found in plants. The purified compound is used in the treatment of mental disorders because of its antidepressive, anxiolytic, and antiepileptic effects....
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Phytoradiotherapy to enhance cancer treatment outcomes with cannabidiol,...
“Despite technological advances in radiation therapy for cancer treatment, many patient populations still experience mediocre survival percentages, local control, and quality of life. Additionally,...
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A novel mechanism of cannabidiol in suppressing ovarian cancer through LAIR-1...
“Cannabidiol (CBD) is a nonpsychoactive cannabinoid compound. It has been shown that CBD can inhibit the proliferation of ovarian cancer cells, but the underlying specific mechanism is unclear. We...
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Delving into The Death Signaling Pathway of Hemp Oil and Gamma Radiation in...
“Many studies reported the diverse therapeutic potential of essential oils, including cancer prevention and treatment. Many mechanisms involved in these processes including antioxidant, antimutagenic...
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Endocannabinoids are potential inhibitors of glioblastoma multiforme...
“Globally, it is evident that glioblastoma multiforme (GBM) is an aggressive malignant cancer with a high mortality rate and no effective treatment options. Glioblastoma is classified as the...
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Characterization of the Antitumor Potential of Extracts of Cannabis sativa...
“Cannabis has been used for decades as a palliative therapy in the treatment of cancer. This is because of its beneficial effects on the pain and nausea that patients can experience as a result of...
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The Anti-Tumorigenic Role of Cannabinoid Receptor 2 in Colon Cancer: A Study...
“The endocannabinoid system, particularly cannabinoid receptor 2 (CB2 in mice and CNR2 in humans), has controversial pathophysiological implications in colon cancer. Here, we investigate the role of...
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A Descriptive Review of Cannabis sativa Patents for Cancer Treatment
“Background: Cannabis use for tumor treatment has been explored in several areas, and its potential for tumor remission is currently being studied after the discovery of the endogenous cannabinoid....
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Phytocannabinoids in Triple Negative Breast Cancer Treatment: Current...
“Triple negative breast cancer (TNBC) represents an aggressive subtype of breast cancer, which is deficient in estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor...
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The synergistic anticancer effect of CBD and DOX in osteosarcoma
“Background: Osteosarcoma is a malignant tumor that can present with pain in the bones, joints, and local masses. The incidence is highest in adolescents, and the most common sites are the distal...
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Gene Profiling of Cannabis-sativa-mediated Apoptosis in Human Melanoma Cells
“Background/aim: Malignant melanoma is an aggressive skin cancer, accounting for the majority of skin cancer deaths. Prognosis is often poor and finding effective treatment remains a challenge....
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Cannabidiol and Cannabis Sativa as a potential treatment in vitro prostate...
“Background: Prostate cancer is the second most frequently occurring carcinoma in males worldwide and one of the leading causes of death in men around the world. Recent studies estimate that over 1.4...
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The protective effect of cannabinoids against colorectal cancer cachexia...
“Cancer cachexia is a multifactorial disorder characterized by weight loss and muscle wasting, and there are currently no FDA-approved medications. In the present study, upregulation of six cytokines...
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Anticancer properties of cannabidiol and Δ9-tetrahydrocannabinol and...
“Introduction: With the legalization of cannabis in multiple jurisdictions throughout the world, a larger proportion of the population consumes cannabis. Several studies have demonstrated anti-tumor...
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Specific cannabinoids revive adaptive immunity by reversing immune evasion...
“Emerging cancers are sculpted by neo-Darwinian selection for superior growth and survival but minimal immunogenicity; consequently, metastatic cancers often evolve common genetic and epigenetic...
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Cannabidiol prevents chemotherapy-induced neuropathic pain by modulating...
“Objectives: This study aimed to investigate the effect of cannabidiol (CBD) on type 4 Toll-like receptors (TLR4), glial cells and pro-inflammatory cytokines during the neuropathic pain induced by the...
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The endocannabinoid system, a new gatekeeper in the pharmacology of human...
“Despite numerous prevention methodologies and treatment options, hepatocellular carcinoma (HCC) still remains as the third leading life-threatening cancer. It is thus pertinent to develop new...
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