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Anti-Tumorigenic Effect of a Novel Derivative of 2-Hydroxyoleic Acid and the...
“Modulation of the endogenous cannabinoid system has been suggested as a potential anticancer strategy. In the search for novel and less toxic therapeutic options, structural modifications of the...
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Cannabigerol (CBG) attenuates mechanical hypersensitivity elicited by...
“Background: Cannabigerol (CBG) is a non-psychoactive phytocannabinoid produced by the plant Cannabis sativa with affinity to various receptors involved in nociception. As a result, CBG is marketed as...
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Oral cannabidiol for prevention of acute and transient chemotherapy-induced...
“Purpose: To assess the safety, dosing, and preventive effects of cannabidiol (CBD) on chemotherapy-induced peripheral neuropathy (CIPN) in patients receiving oxaliplatin- or paclitaxel-based...
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Antitumor Effects of Cannabinoids in Human Pancreatic Ductal Adenocarcinoma...
“Background: Pancreatic cancer is considered a rare type of cancer, but the mortality rate is high. Cannabinoids extracted from the cannabis plant have been interested as an alternative treatment in...
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An Examination of the Anti-Cancer Properties of Plant Cannabinoids in...
“Mesothelioma is an aggressive cancer with limited treatment options and a poor prognosis. Phytocannabinoids possess anti-tumour and palliative properties in multiple cancers, however their effects in...
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Effect of CB2 Stimulation on Gene Expression in Pediatric B-Acute...
“Acute lymphoblastic leukemia type B (B-ALL) is the most common kind of pediatric leukemia, characterized by the clonal proliferation of type B lymphoid stem cells. Important progress in ALL...
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Medical Marijuana Use for Cancer-Related Symptoms among Floridians: A...
“Background: Thirty-six states, including Florida, have legalized marijuana for medical and/or recreational use, yet how it is used and perceived by persons with cancer is not well understood....
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Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by...
“Colorectal cancer (CRC) is the leading cause of cancer deaths worldwide, wherein distant metastasis is the main reason for death. The non-psychoactive phytocannabinoid cannabidiol (CBD) effectively...
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Cannabinoids, Medical Cannabis, and Colorectal Cancer Immunotherapy
“Colorectal cancer is a major public health problem. Unfortunately, currently, no effective curative option exists for this type of malignancy. The most promising cancer treatment nowadays is...
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Association between cannabis use with urological cancers: A population-based...
“Background: Legislation of cannabis use has been approved in many European and North American countries. Its impact on urological cancers is unclear. This study was conducted to explore the...
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In Vitro Anti-Proliferative Activity of Cannabis Extract on Human Cancer Cell...
“Background: Cannabis is classified as a Schedule 5 substance under the Narcotics Act B.E. 2522. Among with various modulatory effects of cannabinoids on body functions, two major cannabinoids are...
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Anticancer activity of Δ9-tetrahydrocannabinol and cannabinol in vitro and in...
“Objective: To investigate the effects of Δ9-tetrahydrocannabinol, the principal psychoactive compound of Cannabis sativa, and cannabinol, a Δ9-tetrahydrocannabinol degradative product, on human...
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γ-Terpinene complexed with β-cyclodextrin attenuates spinal neuroactivity in...
“Objectives: Considering that γ-terpinene (γ-TPN) is a monoterpene found in Cannabis oil, with high lipophilicity and limited pharmacokinetics, our objective was to evaluate whether its complexation...
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Investigation of the Effects of the Endogenous Cannabinoid Anandamide on...
“The present study was carried out to investigate anti-tumoral effects of Anandamide (AEA) in luminal A breast cancer cell line MCF-7. Cell viability was measured by MTT assay and cell index was...
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Evaluation of Sex Differences in the Potential of Δ 9-Tetrahydrocannabinol,...
“Introduction: Cancer patients report nausea as a side effect of their chemotherapy treatment. Using the pre-clinical rodent model of acute nausea-lithium chloride (LiCl)-induced conditioned...
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Hemp ( Cannabis sativa L., Kompolti cv.) and Hop ( Humulus lupulus L.,...
“In this study, essential oils (EOs) and hydrolates (Hys) from Italian hemp (Cannabis sativa L. Kompolti cv.) and hop (Humulus Lupulus L., Chinook cv.) supply chains were chemically characterized and...
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Analysis of Potential Anti-Cancer Effects of Cannabinol and Cannabidiol using...
“Humans produce endocannabinoids that act as neuromodulators in the endocannabinoid system. They bind to Gαi protein-coupled cannabinoid receptors to control the release of many neurotransmitters....
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Cannabinoid Cancer Biology and Prevention
“Plant-based, synthetic, and endogenous cannabinoids have been shown to control a diverse array of biological processes, including regulation of cell fate across cancers. Their promise as broad-based...
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Experience With Medical Marijuana for Cancer Patients in the Palliative Setting
“Objectives: Medical marijuana is a symptom treatment option for palliative cancer patients; however, its useful applications remain limited. The goals of this study were to review the characteristics...
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Practical Considerations for the Use of Cannabis in Cancer Pain...
“Pain is a highly debilitating emotional and sensory experience that significantly affects quality of life (QoL). Numerous chronic conditions, including cancer, are associated with chronic pain. In...
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