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Management of chronic pain with Jalaprakshalana (water-wash) Shodhita...

“Introduction: Pain is a common and complex symptom of cancer having physical, social, spiritual and psychological aspects. Approximately 70%-80% of cancer patients experiences pain, as reported in...

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Cannabidiol exerts anti-proliferative activity via a cannabinoid receptor...

“Colorectal cancer is the third leading cause of cancer incidence and mortality in the United States. Cannabidiol (CBD), the second most abundant phytocannabinoid in Cannabis sativa, has potential use...

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The Effectiveness and Safety of Medical Cannabis for Treating Cancer Related...

“The use of medical cannabis (MC) to treat cancer-related symptoms is rising. However, there is a lack of long-term trials to assess the benefits and safety of MC treatment in this population. In this...

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Cannabinoid Receptor-1 suppresses M2 macrophage polarization in colorectal...

“Cannabinoid receptors, CB1 and CB2, have been implicated as emerging targets for cancer therapy. Herein, we investigated the potential regulation mechanism of CB1 and its implications in colorectal...

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Biological Effects of Cannabidiol on Human Cancer Cells: Systematic Review of...

“This systematic review examine the biological effects of CBD, a major component of therapeutic Cannabis, on human pathological and cancer cell populations of integumentary, gastro-intestinal, genital...

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Protective Effects of Cannabidiol on Chemotherapy-Induced Oral Mucositis via...

“Oral mucositis (OM) is a common complication during chemotherapy characterized by ulceration, mucosa atrophy, and necrosis, which seriously interferes with nutritional intake and oncotherapy...

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Extracellular vesicles of cannabis with high CBD content induce anticancer...

“Plant-derived extracellular vesicles (EVs) have been the topic of interest in recent years due to their proven therapeutic properties. Intact or manipulated plant EVs have shown antioxidant,...

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Cannabidiol and Cannabigerol Inhibit Cholangiocarcinoma Growth In Vitro via...

“Cholangiocarcinoma (CCA) is a rare and highly lethal disease with few effective treatment options. Cannabinoids, cannabidiol (CBD) and cannabigerol (CBG) are non-psychedelic components extracted from...

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Mechanisms of Cannabidiol (CBD) in Cancer Treatment: A Review

“Cannabis sativa L. (Cannabis) and its bioactive compounds, including cannabinoids and non-cannabinoids, have been extensively studied for their biological effects in recent decades. Cannabidiol...

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Cannabidiol Interacts Antagonistically with Cisplatin and Additively with...

“The medical application of cannabidiol (CBD) has been gathering increasing attention in recent years. This non-psychotropic cannabis-derived compound possesses antiepileptic, antipsychotic,...

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In Vitro Effect of Δ9-Tetrahydrocannabinol and Cannabidiol on...

“There is evidence that demonstrates the effect of cannabinoid agonists inhibiting relevant aspects in lung cancer, such as proliferation or epithelial-to-mesenchymal transition (EMT). Most of these...

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Receptor-targeted nanoparticles modulate cannabinoid anticancer activity...

“Δ9-tetrahydrocannabinol (Δ9-THC) is known for its antitumor activity and palliative effects. However, its unfavorable physicochemical and biopharmaceutical properties, including low bioavailability,...

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Cannabis: Chemistry, extraction and therapeutic applications

“Cannabis, a genus of perennial indigenous plants is well known for its recreational and medicinal activities. Cannabis and its derivatives have potential therapeutic activities to treat epilepsy,...

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Therapeutic Potential of Cannabinoids on Tumor Microenvironment: A Molecular...

“The efficacy of chemotherapy depends on the tumor microenvironment. This microenvironment consists of a complex cellular network that can exert both stimulatory and inhibitory effects on tumor...

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The Combination of Δ 9-Tetrahydrocannabinol and Cannabidiol Suppresses...

“Phytocannabinoids represent a promising approach in glioblastoma therapy. Previous work has shown that a combined treatment of glioblastoma cells with submaximal effective concentrations of...

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Investigating the Effects of a Synthetic Cannabinoid on the Pathogenesis of...

“The popularity and usage of synthetic cannabinoids (SCs) are increasing due to their easy accessibility and psychoactive effects worldwide. Studies on cannabinoids on leukemic stem cells (LSC) and...

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Protective Effects of Cannabis sativa on chemotherapy-induced nausea in a...

“Cyclophosphamide is an anticancer and immunosuppressive agent used in the treatment of various malignancies but causing gastrointestinal distress. Cannabis sativa (C. sativa) and its derivatives have...

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Anti-cancer properties of cannflavin A and potential synergistic effects with...

“Introduction: Several studies have shown anti-tumor effects of components present in cannabis in different models. Unfortunately, little is known about the potential anti-tumoral effects of most...

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Cannabidiol Regulates PPARγ-Dependent Vesicle Formation as well as Cell Death...

“Extracts of phytocannabinoids from Cannabis sativa have been studied for therapeutic purposes. Although nonpsychoactive CBD has been studied as a promising anticancer drug because it induces...

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Improved Therapeutic Efficacy of CBD with Good Tolerance in the Treatment of...

“Cannabidiol (CBD), a nonpsychoactive major component derived from Cannabis sativa, widely used in neurodegenerative diseases, has now been proven to have growth inhibitory effects on many tumor cell...

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