Clik here to view.
Unveiling the mechanism of action behind the anti-cancer properties of...
“Breast cancer is the leading cause of cancer-related death in women worldwide. In the last years, cannabinoids have gained attention in the clinical setting and clinical trials with cannabinoid-based...
View ArticleClik here to view.
The effect of cannabis in the treatment of Hodgkin’s lymphoma in a pregnant...
“Purpose: Hodgkin lymphoma (HL) is the fourth most frequent cancer diagnosis among pregnant females. A multidisciplinary team is mandatory to obtain the best treatment and prognosis for the mother and...
View ArticleClik here to view.
Efficacy of cannabinoids against glioblastoma multiforme: A systematic review
“INTRODUCTION : The increased incidence of Glioblastoma Multiforme, the most aggressive and most common primary brain tumour, is evident worldwide. Survival rates are reaching only 15 months due to...
View ArticleClik here to view.
THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma...
“Glioblastoma (GBM) is the most frequent malignant tumor of the central nervous system in humans with a median survival time of less than 15 months. ∆9-Tetrahydrocannabinol (THC) and cannabidiol (CBD)...
View ArticleClik here to view.
Molecular Mechanism of Autophagy and Its Regulation by Cannabinoids in Cancer
“Autophagy is a “self-degradation” process whereby malfunctioned cytoplasmic constituents and protein aggregates are engulfed by a vesicle called the autophagosome, and subsequently degraded by the...
View ArticleClik here to view.
Different Cannabis sativa Extraction Methods Result in Different Biological...
“Cannabis sativa is one of the oldest medicinal plants used by humans, containing hundreds of bioactive compounds. The biological effects and interplay of these compounds are far from fully...
View ArticleClik here to view.
Human laryngeal squamous cell carcinoma cell line release of endogenous...
“The level of the major endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are altered in several types of carcinomas, and are known to regulate tumor growth. Thusly, this study...
View ArticleClik here to view.
Cannabinoid Quinones-A Review and Novel Observations
“A cannabinoid anticancer para-quinone, HU-331, which was synthesized by our group five decades ago, was shown to have very high efficacy against human cancer cell lines in-vitro and against in-vivo...
View ArticleClik here to view.
Cannabidiol converts NFκB into a tumor suppressor in glioblastoma with...
“The transcription factor NFκB drives neoplastic progression of many cancers including primary brain tumors (glioblastoma; GBM). Precise therapeutic modulation of NFκB activity can suppress central...
View ArticleClik here to view.
Cannabidiol Treatment Results in a Common Gene Expression Response Across...
“We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of the prometastatic gene inhibitor of DNA binding 1 (ID1) in cancer cells,...
View ArticleClik here to view.
The Molecular targets of Cannabinoids in the treatment of Cancer and...
“In this review we discuss the emerging evidence for the effectiveness of cannabinoids in the treatment of cancer and inflammation. The remarkable effects complete the traditional evidence for their...
View ArticleClik here to view.
Cannabidiol in Neurological and Neoplastic Diseases: Latest Developments on...
“As the major nonpsychotropic constituent of Cannabis sativa, cannabidiol (CBD) is regarded as one of the most promising therapeutic agents due to its proven effectiveness in clinical trials for many...
View ArticleClik here to view.
Repurposing Cannabidiol as a Potential Drug Candidate for Anti-Tumor Therapies
“In recent years, evidence has accumulated that cannabinoids-especially the non-psychoactive compound, cannabidiol (CBD)-possess promising medical and pharmacological activities that might qualify...
View ArticleClik here to view.
Specific Compositions of Cannabis sativa Compounds Have Cytotoxic Activity...
“Glioblastoma multiforme (GBM) is the most lethal subtype of glioma. Cannabis sativa is used for the treatment of various medical conditions. Around 150 phytocannabinoids have been identified in C....
View ArticleClik here to view.
Cannabinoids pharmacological effects are beyond the palliative effects: CB2...
“Colorectal cancer (CRC) is between the top three occurring cancers worldwide. The anticancer effects of Cannabinoid receptor 2 (CB2) agonist (GW833972A) in the presence and absence of its inverse...
View ArticleClik here to view.
Cannabinoid Receptor Type-2 in B Cells Is Associated with Tumor Immunity in...
“Agents targeting the endocannabinoid system (ECS) have gained attention as potential cancer treatments. Given recent evidence that cannabinoid receptor 2 (CB2R) regulates lymphocyte development and...
View ArticleClik here to view.
Molecular Mechanism of Cannabinoids in Cancer Progression
“Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors eliciting several physiological effects both in the central and peripheral nervous systems and in peripheral...
View ArticleClik here to view.
Anticancer property of Hemp Bioactive Peptides in Hep3B liver cancer cells...
“Foodborne protein hydrolysates exhibit biological activity that may be therapeutic in a number of human disease settings. Hemp peptides (HP) generated by controlled hydrolysis of hemp proteins have a...
View ArticleClik here to view.
Scoping Review and Meta-Analysis Suggests that Cannabis Use May Reduce Cancer...
“Cannabis use reduces the risk of obesity and cannabinoids inhibit chronic inflammation, known causes of cancer.” https://pubmed.ncbi.nlm.nih.gov/33998861/ “In addition, in laboratory studies,...
View ArticleClik here to view.
Cannabidiol Modulates Mitochondrial Redox and Dynamics in MCF7 Cancer Cells:...
“The cannabinoid, cannabidiol (CBD), is part of the plant’s natural defense system that when given to animals has many useful medicinal properties, including activity against cancer cells, modulation...
View Article