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Effect of combined doses of Δ9-tetrahydrocannabinol and cannabidiol or...
“This study evaluated the potential of combined cannabis constituents to reduce nausea. CONCLUSION: Combinations of very low doses of CBD + THC or CBDA + THCA robustly reduce LiCl-induced conditioned...
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[Cannabidiol in cancer treatment].
“Cannabis was used for cancer patients as early as about 2500 years ago. Experimental studies demonstrated tumor-inhibiting activities of various cannabinoids more than 40 years ago. In view of the...
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Use of cannabinoids in cancer patients: A Society of Gynecologic Oncology...
“Tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN) affect the human endocannabinoid system. Cannabinoids reduce chemotherapy induced nausea or vomiting (CINV) and neuropathic pain....
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The role of cannabinoids in the treatment of cancer.
“The aim of this review article is to summarize current knowledge about the role of cannabinoids and cannabinoid receptors in tumor disease modulation and to evaluate comprehensively the use of...
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Cannabis use in pediatric cancer patients: what are they reading? A review of...
“Recent changes to the legal status of marijuana in Canada warrant a review of the information that patients and families are accessing online regarding the role of cannabis in cancer. The aims of the...
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The Endocannabinoid System: A Target for Cancer Treatment.
“In recent years, the endocannabinoid system has received great interest as a potential therapeutic target in numerous pathological conditions. Cannabinoids have shown an anticancer potential by...
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Treatment with Cannabinoids as a Promising Approach for Impairing Fibroblast...
“Endo-, phyto- and synthetic cannabinoids have been proposed as promising anti-cancer agents able to impair cancer cells’ behavior without affecting their non-transformed counterparts. However,...
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The Highs and Lows of Cannabis in Cancer Treatment and Bone Marrow...
“In the last decade, we have observed an increased public and scientific interest in the clinical applications of medical cannabis. Currently, the application of cannabinoids in cancer patients is...
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Cannabinoid Signaling in Glioma Cells.
“Cannabinoids are a group of structurally heterogeneous but pharmacologically related compounds, including plant-derived cannabinoids, synthetic substances and endogenous cannabinoids, such as...
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Targeting GPCRs Against Cardiotoxicity Induced by Anticancer Treatments.
“Novel anticancer medicines, including targeted therapies and immune checkpoint inhibitors, have greatly improved the management of cancers. However, both conventional and new anticancer treatments...
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Cannabinoid receptor expression in non-small cell lung cancer. Effectiveness...
“Patients with non-small cell lung cancer (NSCLC) develop resistance to antitumor agents by mechanisms that involve the epithelial-to-mesenchymal transition (EMT). This necessitates the development...
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Inhibition of autophagic flux differently modulates cannabidiol-induced death...
“Radiotherapy combined with chemotherapy is the major treatment modality for human glioblastoma multiforme (GBM). GBMs eventually relapse after treatment and the average survival of GBM patients is...
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The Endocannabinoid System Alleviates Pain in a Murine Model of...
“Metastatic breast cancer is prevalent worldwide, and one of the most common sites of metastasis are long bones. Of patients with disease, the major symptom is pain, yet current medications fail to...
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Cannabinoids and Hormone Receptor-Positive Breast Cancer Treatment.
“Breast cancer (BC) is the most common cancer in women worldwide. Approximately 70-80% of BCs express estrogen receptors (ER), which predict the response to endocrine therapy (ET), and are therefore...
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Insight of Druggable Cannabinoids against Estrogen Receptor β in Breast Cancer.
“Breast cancer (BC) is the second most prevalent cancer worldwide. Estrogen receptor beta (ERβ) is an essential protein of breast cells to suppress estrogen induced uncontrolled proliferation. Thus...
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Hempseed Lignanamides Rich-Fraction: Chemical Investigation and Cytotoxicity...
“The weak but noteworthy presence of (poly)phenols in hemp seeds has been long overshadowed by the essential polyunsaturated fatty acids and digestible proteins, considered responsible for their high...
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Cannabinoids as an Alternative Option for Conventional Analgesics in Cancer...
“The global cancer burden is significantly increasing at an alarming rate affecting patients, relatives, communities, and health-care system. Cancer patients require adequate pain relief and palliative...
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The effects of cannabinoids on glioblastoma growth: A systematic review with...
“Glioblastoma multiforme (GBM) is the most frequent and aggressive malignant brain tumour, with a poor prognosis despite available surgical and radio-chemotherapy, rising the necessity for searching...
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High expectations: The landscape of clinical trials of medical marijuana in...
“Given the infancy and evolving complexity of medicinal marijuana, an evolving political landscape, and the growing frequency of its use in cancer care, it is important for oncologists to be actively...
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Editorial: The Canonical and Non-Canonical Endocannabinoid System as a Target...
“The endocannabinoid system (ECS) comprises the canonical receptor subtypes CB1R and CB2R and endocannabinoids (anandamide, AEA and 2-arachidonoylglycerol, 2-AG), and a “non-canonical” extended...
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