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The Effects of Dosage-Controlled Cannabis Capsules on Cancer-Related Cachexia...
“Cancer-related cachexia and anorexia syndrome (CACS) is a common phenomenon in cancer patients. Cannabis has been suggested to stimulate appetite but research on this issue has yielded mixed results....
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Cannabidiol directly targets mitochondria and disturbs calcium homeostasis in...
“Anticancer properties of non-psychoactive cannabinoid cannabidiol (CBD) have been demonstrated on tumors of different histogenesis. Different molecular targets for CBD were proposed, including...
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Antitumor Activity of Abnormal Cannabidiol and Its Analog O-1602 in...
“Cannabinoids exhibit anti-inflammatory and antitumorigenic properties. Contrary to most cannabinoids present in the Cannabis plant, some, such as O-1602 and abnormal cannabidiol, have no or only...
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The endocannabinoid system: Novel targets for treating cancer induced bone pain.
“Treating Cancer-induced bone pain (CIBP) continues to be a major clinical challenge and underlying mechanisms of CIBP remain unclear. Recently, emerging body of evidence suggested the endocannabinoid...
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WIN55,212-2-Induced Expression of Mir-29b1 Favours the Suppression of...
“WIN55,212-2 (WIN) is a synthetic agonist of cannabinoid receptors that displays promising antitumour properties. The aim of this study is to demonstrate that WIN is able to block the migratory...
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Cannabinoid receptor 2‑selective agonist JWH015 attenuates bone cancer pain...
“Bone cancer pain (BCP) is a severe complication of advanced bone cancer. Although cannabinoid receptor 2 (CB2) agonists may have an analgesic effect, the underlying mechanism remains unclear. CB2...
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Prevalence and predictors of cannabis use among men receiving...
“Prostate cancer patients receiving androgen-deprivation therapy (ADT) often experience a combination of disease symptoms and treatment side effects. The therapeutic use of cannabis to alleviate...
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Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives...
“The anticancer effects of the omega-3 long chain polyunsaturated fatty acids (LCPUFA), EPA and DHA may be due, at least in part, to conversion to their respective endocannabinoid derivatives,...
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Non-prescription cannabis use for symptom management amongst women with...
“To evaluate interest in and patterns of use of non-prescription cannabis products for symptom management amongst gynecologic cancer patients living in states with legal access to medical and...
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Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer.
“According to recent studies, Cannabidiol (CBD), one of the main components of Cannabis sativa, has anticancer effects in several cancers. However, the exact mechanism of CBD action is not currently...
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Monocyclic Quinone Structure-Activity Patterns: Synthesis of Catalytic...
“The monocyclic 1,4-benzoquinone, HU-331, the direct oxidation product of cannabidiol, inhibits the catalytic activity of topoisomerase II but without inducing DNA strand breaks or generating free...
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Cannabidiol-from Plant to Human Body: A Promising Bioactive Molecule with...
“Cannabis sativa L. is a plant long used for its textile fibers, seed oil, and oleoresin with medicinal and psychoactive properties. It is the main source of phytocannabinoids, with over 100...
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Exploring cancer survivors’ attitudes, perceptions, and concerns about using...
“The purpose of this study is to gain a greater understanding of cancer survivors’ attitudes, perspectives, and concerns about medical cannabinoids (MCs) for cancer symptom and side effect management....
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Investigation of the Involvement of the Endocannabinoid System in...
“Transcutaneous electrical nerve stimulation (TENS) promotes antinociception by activating the descending pain modulation pathway and consequently releasing endogenous analgesic substances. In...
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Long-term benefit from immune modulation and anti-inflammatory treatment in...
“A 64 year old male heating engineer was investigated for a persistent cough and found to have epithelioid mesothelioma with pleural effusion, lung nodules and increased thoracic lymph nodes. He...
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An Open-Label Pilot Study Testing the Feasibility of Assessing Total Symptom...
“There is considerable interest in the use of cannabinoids for symptom control in palliative care, but there is little high-quality evidence to guide clinical practice. Objectives: Assess the...
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CBD loaded microparticles as a potential formulation to improve paclitaxel...
“Cannabidiol (CBD) has emerged as a potential agent for breast cancer management. In this work, the potential use of cannabidiol in solution (CBDsol) and encapsulated in polymeric microparticles when...
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Oral medicinal cannabinoids to relieve symptom burden in the palliative care...
“Despite improvements in medical care, patients with advanced cancer still experience substantial symptom distress. There is increasing interest in the use of medicinal cannabinoids, but there is...
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Management of chronic pain with Jalaprakshalana (water-wash) Shodhita...
“Pain is a common and complex symptom of cancer having physical, social, spiritual and psychological aspects. Approximately 70%-80% of cancer patients experiences pain, as reported in India. Ayurveda...
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Potential role of cannabidiol for seizure control in a patient with recurrent...
“Glioma-related epilepsy significantly impact on patients’ quality of life, and can often be difficult to treat. Seizures cause significant morbidity for example neurocognitive deterioration, which may...
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