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Cannabinoids as a Potential New and Novel Treatment for Melanoma: A Pilot...
“Malignant melanoma is a complex malignancy with significant morbidity and mortality. The incidence continues to rise, and despite advances in treatment, the prognosis is poor. Thus, it is necessary...
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Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer.
“Cannabinoid extracts may have anticancer properties, which can improve cancer treatment outcomes. The aim of this review is to determine the potentially utility of cannabinoids in the treatment of...
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Synthetic Cannabinoids Influence the Invasion of Glioblastoma Cell Lines in a...
“The current treatment of glioblastoma is not sufficient, since they are heterogeneous and often resistant to chemotherapy. Earlier studies demonstrated effects of specific cannabinoid receptor (CB)...
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A Comprehensive Review of Cannabis in Patients with Cancer: Availability in...
“As the legalization of medical cannabis continues across the USA, oncology care providers will be increasingly asked to provide recommendations regarding its use in the cancer setting. In this...
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Role of miRNA in the regulation of cannabidiol-mediated apoptosis in...
“Neuroblastoma (NBL) is one of the most common childhood cancers that originate from the immature nerve cells of the sympathetic system. Studies with NBL cancers have also shown that miRNAs are...
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New Prospect for Cancer Cachexia: Medical Cannabinoid.
“Cachexia is a common term for the wasting symptoms which may appear in almost every chronic illness, such as AIDS, tuberculosis, and cancer. Cancer cachexia (CCA) is a result of the interaction...
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Cannabinoids: the lows and the highs of chemotherapy-induced nausea and...
“Despite remaining one of the most widely abused drugs worldwide, Cannabis sativa exhibits remarkable medicinal properties. The phytocannabinoids, cannabidiol and Δ-9-tetrahydrocannabinol, reduce...
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Synthetic Cannabinoid Activity Against Colorectal Cancer Cells
“Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide, and new therapeutic strategies are still required. Here we screened a synthetic cannabinoid library to identify...
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On the influence of cannabinoids on cell morphology and motility of...
“The mechanisms behind the anti-tumoral effects of cannabinoids by impacting the migratory activity of tumor cells are only partially understood. Previous studies demonstrated that cannabinoids...
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Dronabinol for the Treatment of Paraneoplastic Night Sweats in Cancer...
“Night sweats significantly impact the quality of life for cancer patients and are often resistant to treatment. Cannabinoids have been shown to modulate cytokine activity and produce hypothermia in...
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Cannabinoids: a new approach for pain control?
“To analyze available data related to the use of cannabinoids in medicine, with a special focus on pain management in cancer. The use of cannabis for medical purposes is growing but there are still...
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Inhibition of ATM kinase upregulates levels of cell death induced by...
“Despite advances in glioblastoma (GBM) therapy, prognosis of the disease remains poor with a low survival rate. Cannabidiol (CBD) can induce cell death and enhance radiosensitivity of GBM but not...
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The Endocannabinoid System, Our Universal Regulator
“The endocannabinoid system (ECS) plays a very important role in the human body for our survival. This is due to its ability to play a critical role in maintaining the homeostasis of the human body,...
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CBN: The cancer fighting Cannabinoid
“CBN, cannabinol, is a mildly psychoactive cannabinoid found within the cannabis plant. We examine the very complex mechanisms that give allowance for this cannabinoids entrance into the cell membrane...
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Striking lung cancer response to self-administration of cannabidiol: A case...
“In spite of new drugs, lung cancer is associated with a very poor prognosis. While targeted therapies are improving outcomes, it is not uncommon for many patients to have only a partial response, and...
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Characterization of Cancer-Induced Nociception in a Murine Model of Breast...
“Severe and poorly treated pain often accompanies breast cancer. Thus, novel mechanisms involved in breast cancer-induced pain should be investigated. Then, it is necessary to characterize animal...
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Members of the endocannabinoid system are distinctly regulated in...
“Preclinical studies have demonstrated that the endocannabinoid system (ECS) plays an important role in the protection against intestinal inflammation and colorectal cancer (CRC); however, human data...
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Impact of Medical Cannabis on Patient-Reported Symptoms for Patients With...
“Minnesota’s medical cannabis program is unique, in that it routinely collects patient-reported scores on symptoms. This article focuses on changes in symptom severity reported by patients with cancer...
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The onus of cannabinoids in interrupting the molecular odyssey of breast...
“Cannabinoids, commonly used for medicinal and recreational purposes, consist of various complex hydrophobic molecules obtained from Cannabis sativa L. Acting as an inhibitory molecule; they have been...
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Future Aspects for Cannabinoids in Breast Cancer Therapy.
“Cannabinoids (CBs) from Cannabis sativa provide relief for tumor-associated symptoms (including nausea, anorexia, and neuropathic pain) in the palliative treatment of cancer patients. Additionally,...
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