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At 70, Singer Olivia Newton-John Using Cannabis To Treat Cancer.
“At 70, Singer Olivia Newton-John Using Cannabis To Treat Cancer. Olivia Newton-John says she has been diagnosed with cancer for the third time in three decades. Newton-John says she’s “treating it...
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Report of Objective Clinical Responses of Cancer Patients to...
“Cannabinoids are widely used in the management of pain, nausea and cachexia in cancer patients. However, there has been no objective clinical evidence of any anticancer activity yet. The aim of this...
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Medical Cannabis Use by Hodgkin Lymphoma Patients: Experience of a Single...
“Hodgkin lymphoma (HL) is one of the most curable malignancies. Despite its effectiveness, chemotherapy is often associated with adverse events (AEs) such as nausea, anorexia, and impairment of...
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Light-activatable cannabinoid prodrug for combined and target-specific...
“Cannabinoids are emerging as promising antitumor drugs. However, complete tumor eradication solely by cannabinoid therapy remains challenging. In this study, we developed a far-red light activatable...
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Up-regulation of heme oxygenase-1 expression and inhibition of...
“Aberrant proliferation and migration of vascular smooth muscle cells (VSMC) have been closely linked to the development and progression of cardiovascular and cancer diseases. The cytoprotective...
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Synthetic cannabinoids nano-micelles for the management of triple negative...
“Triple-negative breast cancer (TNBC) is a highly heterogeneous disease with poor prognosis and inadequate therapeutic outcome. This contribution reports the use of a cannabinoid derivative,...
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Oncology Clinicians and the Minnesota Medical Cannabis Program: A Survey on...
“Medical cannabis has been available in the State of Minnesota since July 2015 through the Minnesota Medical Cannabis Program (MMCP). Objectives: Our study aimed to delineate oncology providers’ views...
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The endocannabinoid signaling system in cancer
“Changes in lipid metabolism are intimately related to cancer. Several classes of bioactive lipids play roles in the regulation of signaling pathways involved in neoplastic transformation and tumor...
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Naturally occurring compounds as pancreatic cancer therapeutics.
“Naturally occurring small molecule compounds have long been in the spotlight of pancreatic cancer research as potential therapeutics to prevent cancer progression and sensitize chemoresistant tumors....
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miR-23b-3p and miR-130a-5p affect cell growth, migration and invasion by...
“Gastric cancer (GC) is the most common malignancy and third leading cause of cancer mortality worldwide. The identification of a sensitive biomarker as well as effective therapeutic targets for the...
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Cannabidiolic Acid-Mediated Interference with AP-1 Transcriptional Activity...
“We reported that cannabidiolic acid (CBDA), a non-psychotropic constituent of fiber-type cannabis plants, down-regulates the mRNA expression of cyclooxygenase-2 (COX-2) in highly aggressive...
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An Integrated Review of Cannabis and Cannabinoids in Adult Oncologic Pain...
“The objective of this paper is to review the available literature regarding the use of cannabis and cannabinoids in adult oncologic pain management. RESULTS: The final number of articles included is...
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Health-related quality of life across cancer cachexia stages.
“Cancer cachexia (CC) is common in advanced cancer and is accompanied by negative effects on health-related quality of life (HRQOL). However, methods to identify the impact of CC on HRQOL are limited....
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Cannabis-related cognitive impairment: a prospective evaluation of possible...
“In patients with cancer, the use of medical cannabis has increased significantly during the recent years. There is evidence that cannabis consumption may affect cognitive performance; however, this...
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Cannabinoid receptor expression in estrogen-dependent and...
“The lack of good diagnostic/prognostic biomarkers and the often late presentation of endometrial cancer (EC) hinders the amelioration of the morbidity and mortality rates associated with this...
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Cannabis for cancer – illusion or the tip of an iceberg: a review of the...
“A flowering plant of variegated ingredients and psychoactive qualities, Cannabis has long been used for medicinal and recreational purposes. Regulatory approvals have been gained across a broad range...
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Cannabidiol Affects Extracellular Vesicle Release, miR21 and miR126, and...
“Glioblastoma multiforme (GBM) is the most common and aggressive form of primary malignant brain tumor in adults, with poor prognosis. Extracellular vesicles (EVs) are key-mediators for cellular...
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Cannabis sativa L. and Nonpsychoactive Cannabinoids: Their Chemistry and Role...
“In the last decades, a lot of attention has been paid to the compounds present in medicinal Cannabis sativa L., such as Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD), and their effects on...
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Cannabidiol-induced apoptosis is mediated by activation of Noxa in human...
“Cannabidiol (CBD), one of the compounds present in the marijuana plant, has anti-tumor properties, but its mechanism is not well known. This study aimed to evaluate the apoptotic action of CBD in...
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Prospects for the Use of Cannabinoids in Oncology and Palliative Care...
“There is an increased interest in the use of cannabinoids in the treatment of symptoms in cancer and palliative care patients. Their multimodal action, in spite of limited efficacy, may make them an...
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