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Cannabinoid receptor CB1 regulates STAT3 activity and its expression dictates...
“Herein we show that a majority of human brain tumor samples and cell lines over-expressed cannabinoid receptor CB1 as compared to normal human astrocytes (NHA), while uniformly expressed low levels...
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Cannabisin B induces autophagic cell death by inhibiting the AKT/mTOR pathway...
“This study investigates the anticancer properties of cannabisin B, purified from hempseed hull, in HepG2 human hepatoblastoma cells. The results indicate that cannabisin B significantly inhibited cell...
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Marijuana kills brain cancer, new study confirms
“The active molecules in cannabis kill brain cancer — another study has revealed.” “Scientists using an extract of whole-plant marijuana rich in pot’s main psychoactive ingredient THC as well as...
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The use of cannabinoids as anticancer agents.
“It is well-established that cannabinoids exert palliative effects on some cancer-associated symptoms. In addition evidences obtained during the last fifteen years support that these compounds can...
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The dual effects of delta(9)-tetrahydrocannabinol on cholangiocarcinoma...
“Currently, only gemcitabine plus platinum demonstrates the considerable activity for cholangiocarcinoma. The anticancer effect of Delta (9)-tetrahydrocannabinol (THC), the principal active component...
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Opposing actions of endocannabinoids on cholangiocarcinoma growth:...
“Cholangiocarcinomas are devastating cancers of biliary origin with limited treatment options… Marijuana and its derivatives have been used in medicine for many centuries, and presently there is an...
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Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the...
“Cholangiocarcinomas are devastating cancers of intrahepatic and extrahepatic origin that are increasing in both their worldwide incidence and mortality rates. Conventional chemotherapy and radiation...
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The endocannabinoid anandamide inhibits cholangiocarcinoma growth via...
“Cholangiocarcinomas are cancers that have poor prognosis and limited treatment options. Marijuana and its derivatives have been used in medicine for many centuries. …cannabinoids might be effective...
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Anandamide exerts its antiproliferative actions on cholangiocarcinoma by...
“We have previously shown that AEA exerts growth-suppressing effects on cholangiocarcinoma by inducing apoptosis. At the time, we assumed that AEA was acting via a receptor-independent mechanism....
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Phytocannabinoids for Cancer Therapeutics: Recent Updates and Future Prospects.
“Phytocannabinoids (pCBs) are lipid-soluble phytochemicals present in the plant, Cannabis sativa L. and non-cannabis plants which have a long history in traditional and recreational medicine. The plant...
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Bone cell-autonomous contribution of type 2 cannabinoid receptor to breast...
“The cannabinoid type 2 receptor (CB2) has previously been implicated as a regulator of tumour growth, bone remodelling and bone pain. However, very little is known about the role of the skeletal CB2...
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The Use of Styrene Maleic Acid Nanomicelles Encapsulating the Synthetic...
“Synthetic cannabinoid WIN55,212-2 (WIN) has shown a promise as an anticancer agent but causes psychoactive side-effects. In the present study, nano-micelles of styrene maleic acid (SMA)-conjugated WIN...
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On the effects of CP 55-940 and other cannabinoid receptor agonists in C6 and...
“Cannabinoid receptor (CBs) agonists affect the growth of tumor cells via activation of deadly cascades. The spectrum of action of these agents and the precise role of the endocannabinoid system (ECS)...
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Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in...
“THC may be useful in the palliation of chemosensory alterations and to improve food enjoyment for cancer patients.” http://www.ncbi.nlm.nih.gov/pubmed/21343383
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The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of...
“One of the most exciting areas of current research in the cannabinoid field is the study of the potential application of these compounds as antitumoral drugs. Here, we describe the signaling pathway...
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Cannabis and Cannabinoids (PDQ®) Patient Version
“Cannabis, also known as marijuana, is a plant grown in many parts of the world which produces a resin containingcompounds called cannabinoids. Some cannabinoids are psychoactive (acting on the brain...
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Cannabis and Cannabinoids (PDQ®) Health Professional Version
“This complementary and alternative medicine (CAM) information summary provides an overview of the use of Cannabis and its components as a treatment for people with cancer-related symptoms caused by...
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The adverse effects of cannabinoids: implications for use of medical marijuana
“Wang and colleagues present a systematic review of the research on adverse effects of medical cannabis use. The authors found that most of the adverse events reported in the randomized clinical...
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Endocannabinoids and Cancer.
“A large body of evidence shows that cannabinoids, in addition to their well-known palliative effects on some cancer-associated symptoms, can reduce tumour growth in animal models of cancer. They do...
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Evaluation of cannabinoid CB1 and CB2 receptors expression in mobile tongue...
“Cannabinoid receptors (CB1R and CB2R) constitute essential members of the endocannabinoid system (ECS) which participates in many different functions indispensable to homeostatic regulation in several...
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