Clik here to view.
Inhibition of Myeloma Cell Function by Cannabinoid-Enriched Product...
“Multiple myeloma is a hematological cancer caused by the uncontrolled proliferation of abnormal plasma cells in the bone marrow, leading to excessive immunoglobulin production. Our study aimed to...
View ArticleClik here to view.
Cannabinoid combination targets NOTCH1-mutated T-cell acute lymphoblastic...
“In T-cell acute lymphoblastic leukemia (T-ALL), more than 50% of cases display autoactivation of Notch1 signaling, leading to oncogenic transformation. We have previously identified a specific...
View ArticleClik here to view.
The Efficacy of Cannabis in Oncology Patient Care and Its Anti-Tumor Effects
“As the legalization of medical cannabis expands across several countries, interest in its potential advantages among cancer patients and caregivers is burgeoning. However, patients seeking to...
View ArticleClik here to view.
Exploring the therapeutic potential of cannabinoids in cancer by modulating...
“For centuries, cannabinoids have been utilized for their medicinal properties, particularly in Asian and South-Asian countries. Cannabis plants, known for their psychoactive and non-psychoactive...
View ArticleClik here to view.
Molecular Targets of Minor Cannabinoids in Breast Cancer: In Silico and In...
“Background: Breast cancer therapy has been facing remarkable changes. Classic treatments are now combined with other therapies to improve efficacy and surpass resistance. Indeed, the emergence of...
View ArticleClik here to view.
A new cannabigerol derivative, LE-127/2, induces autophagy mediated cell...
“Despite the targeted- and immunotherapies used in the past decade, survival rate among patients with metastatic melanoma remains low, therefore, melanoma is responsible for the majority of skin...
View ArticleClik here to view.
Preparation of a nanoemulsion containing active ingredients of cannabis...
“Recently, the anti-tumor effects of cannabis extract on various cancers have attracted the attention of researchers. Here, we report a nanoemulsion (NE) composition designed to enhance the delivery...
View ArticleClik here to view.
Exploring the Potential of Synthetic Cannabinoids: Modulation of Biological...
“Colorectal cancer (CRC) is a global problem. Oncology currently practices conventional methods of treating this carcinoma, including surgery, chemotherapy, and radiotherapy. Unfortunately, their...
View ArticleClik here to view.
DNA damage and cell death in human oral squamous cell carcinoma cells: The...
“Objective: The present study examined the in vitro effects on oral squamous cell carcinoma cells (HSC-3) of cannabidiol (CBD), the main chemical component of Cannabis, proposed as a novel adjuvant...
View ArticleClik here to view.
In Vitro Antitumor Effect of Oils Rich in CBD and THC Cannabis Extract in...
“Prostate cancer is one of the leading causes of cancer-related deaths worldwide, even when diagnosed at an early stage in humans and dogs. Dogs have a significant incidence of spontaneous prostate...
View ArticleClik here to view.
Effects of Cannabidiol (CBD) on Doxorubicin-Induced Anxiety and...
“Background: Post-treatment side effects of chemotherapy can include cognitive deficits commonly known as Chemo-brain. The treatment of patients with Doxorubicin (DOX), one of the most widely used...
View ArticleClik here to view.
The Endocannabinoid System of the Nervous and Gastrointestinal Systems...
“Background/Objectives: Cisplatin, a common chemotherapy agent, is well known to cause severe side effects in the gastrointestinal and nervous systems due to its toxic and pro-inflammatory effects....
View ArticleClik here to view.
The molecular anti-metastatic potential of CBD and THC from Lebanese Cannabis...
“The medicinal plant Cannabis sativa L. (C. sativa) is currently being extensively studied to determine the full extent of its therapeutic pharmacological potential. Δ9-tetrahydocannabinol (THC) and...
View ArticleClik here to view.
Therapeutic potentials of cannabidiol: Focus on the Nrf2 signaling pathway
“Cannabidiol (CBD), a cannabinoid that does not create psychoactive activities, has been identified as having a multitude of therapeutic benefits. This study delves into the chemical properties,...
View ArticleClik here to view.
Improved Therapeutic Efficacy of Doxorubicin Chemotherapy With Cannabidiol in...
“Background: High dose chemotherapy is one of the therapeutic strategies for breast cancer and doxorubicin (DOX) as a chemotherapy agent is widely used. DOX indication is limited due to its...
View ArticleClik here to view.
Targeting carbohydrate metabolism in colorectal cancer – synergy between...
“Chemotherapy is a therapy of choice for many cancers. However, it is often inefficient for long-term patient survival and is usually accompanied by multiple adverse effects. The adverse effects are...
View ArticleClik here to view.
Cannabidiol and fluorinated derivative anti-cancer properties against...
“Background: Glioblastoma multiforme (GBM) is an aggressive cancer with poor prognosis, partly due to resistance to the standard chemotherapy treatment, temozolomide (TMZ). Phytocannabinoid...
View ArticleClik here to view.
Cannabidiol (CBD) Protects Lung Endothelial Cells from Irradiation-Induced...
“Objective: Radiotherapy, which is commonly used for the local control of thoracic cancers, also induces chronic inflammatory responses in the microvasculature of surrounding normal tissues such as...
View ArticleClik here to view.
Combinatorial effects of cannabinoid receptor 1 and 2 agonists on...
“Breast cancer is the most common cancer diagnosed in women worldwide. However, the effective treatment for breast cancer progression is still being sought. The activation of cannabinoid receptor (CB)...
View ArticleClik here to view.
Discovery of Ring-Annulated Analogues of Cannabidiol as Potential Anticancer...
“Cannabidiol (CBD) is a nonpsychoactive cannabinoid derived from Cannabis sativa and its potential therapeutic effects extend beyond its well-known antiepileptic properties. Exploring CBD and its...
View Article